The expected paCO2 at maximal can be calculated from a simple formula.
The arterial paCO2 at maximal compensation has been measured in many patients with a metabolic acidosis. A consistent relationship between bicarbonate level and PaCO2 has been found.
If the measured HCO3 is 12 mmols/l, then the expected pCO2 (at maximal compensation) would be: (1.5 x 12) + 8 = 18 + 8 = 26 mmHg.
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